Article
EPAS1 gene variants are associated with sprint/power athletic performance in two cohorts of European athletes.
BMC genomics - 18 May 2014
Voisin Sarah, Cieszczyk Pawel, Pushkarev Vladimir P, Dyatlov Dmitry A, Vashlyayev Boris F, Shumaylov Vladimir A, Maciejewska-Karlowska Agnieszka, Sawczuk Marek, Skuza Lidia, Jastrzebski Zbigniew, Bishop David J, Eynon Nir
Abstract excerpt
BACKGROUND: The endothelial PAS domain protein 1 (EPAS1) activates genes that are involved in erythropoiesis and angiogenesis, thus favoring a better delivery of oxygen to the tissues and is a plausible candidate to influence athletic performance. Using innovative statistical methods we compared genotype distributions and interactions of EPAS1 SNPs rs1867785, rs11689011, rs895436, rs4035887 and rs1867782 between...