Article
Comparison of measures of marker informativeness for ancestry and admixture mapping.
BMC genomics - 20 Dec 2011
Ding Lili, Wiener Howard, Abebe Tilahun, Altaye Mekbib, Go Rodney C P, Kercsmar Carolyn, Grabowski Greg, Martin Lisa J, Khurana Hershey Gurjit K, Chakorborty Ranajit, Baye Tesfaye M
Abstract excerpt
BACKGROUND: Admixture mapping is a powerful gene mapping approach for an admixed population formed from ancestral populations with different allele frequencies. The power of this method relies on the ability of ancestry informative markers (AIMs) to infer ancestry along the chromosomes of admixed individuals. In this study, more than one million SNPs from HapMap databases and simulated data have been interrogated...
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