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Article

Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice.

Internal medicine journal - 1 Oct 2005

Gearry R B, Barclay M L, Roberts R L, Harraway J, Zhang M, Pike L S, George P M, Florkowski C M

Abstract excerpt

BACKGROUND: Azathioprine and 6-mercaptopurine (6-MP) are well established for the treatment of inflammatory bowel disease (IBD). Assessing thiopurine methyltransferase (TPMT) status has been recommended to reduce the risk of serious toxicity. Measuring red blood cell (RBC) 6-thioguanine nucleotid...

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Source

Identifiers

PMID: 16207256
DOI: 10.1111/j.1445-5994.2005.00904.x

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16207256-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice.PMID 16207256Read ↗

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