Article
Retrospective analysis of case-control studies when the population is in Hardy-Weinberg equilibrium.
Statistics in medicine - 15 Nov 2005
Cheng K F, Lin W J
Abstract excerpt
Association analysis of genetic polymorphisms has been mostly performed in a case-control setting in connection with the traditional logistic regression analysis. However, in a case-control study, subjects are recruited according to their disease status and their past exposures are determined. Thus the natural model for making inference is the retrospective model. In this paper, we discuss some retrospective...
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