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Article

On information coded in gene-environment independence in case-control studies.

American journal of epidemiology - 15 Sept 2011

Chen Hua Yun, Chen Jinbo

Abstract excerpt

For analysis of case-control genetic association studies, it has recently been shown that gene-environment independence in the population can be leveraged to increase efficiency for estimating gene-environment interaction effects in comparison with the standard prospective analysis. However, for the special case in which data on the binary phenotype and genetic and environmental risk factors can be summarized in...

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Identifiers

PMID: 21828372
DOI: 10.1093/aje/kwr153
PMCID: PMC3166709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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