Article
Long-term gene expression using the lentiviral vector in rat chondrocytes.
Clinical orthopaedics and related research - 1 Oct 2005
Lu Fei-Zhou, Kitazawa Yusuke, Hara Yuko, Jiang Jian-Yuan, Li Xiao-Kang
Abstract excerpt
The optimal approach to a long-term stable transgene expression in chondrocytes has not been established. Recently, lentiviral vectors have been used for transfection of some cultured cell lines. Our study tests the hypothesis that lentiviral vectors lead to longer gene expression in primary chondrocytes. We transfected lentiviral and adenoviral vectors carrying the green fluorescence protein gene to chondrocytes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.