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Article

Improving the iMM904 S. cerevisiae metabolic model using essentiality and synthetic lethality data.

BMC systems biology - 29 Dec 2010

Zomorrodi Ali R, Maranas Costas D

Abstract excerpt

BACKGROUND: Saccharomyces cerevisiae is the first eukaryotic organism for which a multi-compartment genome-scale metabolic model was constructed. Since then a sequence of improved metabolic reconstructions for yeast has been introduced. These metabolic models have been extensively used to elucidate the organizational principles of yeast metabolism and drive yeast strain engineering strategies for targeted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21190580
DOI: 10.1186/1752-0509-4-178
PMCID: PMC3023687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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