Article
Helicase89B is a Mot1p/BTAF1 homologue that mediates an antimicrobial response in Drosophila.
EMBO reports - 1 Nov 2005
Yagi Yoshimasa, Ip Y Tony
Abstract excerpt
We have identified a novel component, Helicase89B, that is required for the inducible antimicrobial response in Drosophila larvae by means of a P-element insertional genetic screen. Helicase89B belongs to the Mot1p/BTAF1 subfamily of SNF2-like ATPases. This subfamily can interact with TATA-binding proteins, but whether the interaction leads to gene activation or repression is being debated. We found that...
Topics
- Animals
- Chromosomal Proteins, Non-Histone
- DNA Helicases
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Gene Expression Profiling
- Gene Expression Regulation
- Immunity
- Larva
- Mutation
- Signal Transduction
- TATA-Binding Protein Associated Factors
- Transcription Factor TFIID
- Transcription Factors
- Transcription, Genetic
- Transcriptional Activation