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Article

Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers.

Clinical pharmacology and therapeutics - 1 Oct 2005

Chung Jae-Yong, Cho Joo-Youn, Yu Kyung-Sang, Kim Jung-Ryul, Oh Dal-Seok, Jung Hye-Ryung, Lim Kyoung-Soo, Moon Ki-Ho, Shin Sang-Goo, Jang In-Jin

Abstract excerpt

BACKGROUND: Pitavastatin is a potent, newly developed 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor for the treatment of hyperlipidemia. We characterized the effects of organic anion transporting polypeptide 1 B 1 (OATP 1 B 1) alleles *1a, *1b, and *15 on the pharmacokinetics of pitavastatin. METHODS: Twenty-four healthy Korean volunteers who had previously participated in a pharmacokinetic study of...

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Identifiers

PMID: 16198653
DOI: 10.1016/j.clpt.2005.07.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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