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Article

The C. elegans lethal gut-obstructed gob-1 gene is trehalose-6-phosphate phosphatase.

Developmental biology - 1 Nov 2005

Kormish Jay D, McGhee James D

Abstract excerpt

We identified the gob-1 (gut-obstructed) gene in a forward genetic screen for intestinal defects in the nematode Caenorhabditis elegans. gob-1 loss of function results in early larval lethality, at least in part because of a blocked intestinal lumen and consequent starvation. The gob-1 gene is first expressed in the 8E cell stage of the embryonic intestine, and the GATA factor ELT-2 is sufficient but not...

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PMID: 16197937
DOI: 10.1016/j.ydbio.2005.08.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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