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Article

Antitumor bioactivity of adenovirus-mediated p27mt in colorectal cancer cell line SW480.

World journal of gastroenterology - 14 Oct 2008

Sun Ze-Qun, Deng Chang-Sheng, Xu Shao-Yong, Du Yong

Abstract excerpt

AIM: To explore the antitumor bioactivity of adenovirus-mediated mutant type p27(kip1) gene in a colorectal cancer cell line SW480. METHODS: We constructed recombinant adenovirus vector expressing a mutant type p27(kip1) gene (ad-p27mt), with mutation of Thr-187/Pro-188 (ACGCCC) to Met-187/Ile-188 (ATGATC), and transduced into SW480 cells. Then we detected expression of p27, Bcl-2 and Bax protein in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18855981
DOI: 10.3748/wjg.14.5827
PMCID: PMC2751892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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