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Article

Post-transcriptional regulation of the human transforming growth factor-beta 1 gene.

1 Jul 1992

Abstract excerpt

Since many lines of evidence suggest that expression of the transforming growth factor-beta 1 (TGF-beta 1) gene may be regulated post-transcriptionally, we examined the effect of the 5'-untranslated region (UTR) of this gene on TGF-beta 1 expression. For this purpose, fragments of the 840-nucleotide highly GC-rich TGF-beta 1 5'-UTR were inserted into the 5'-UTR of the structural gene for human growth hormone...

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PMID: 1618868
DOI: 10.1016/s0021-9258(18)42270-3

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