Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of alcohol consumption and gene polymorphisms of ADH2 and ALDH2 on hepatocellular carcinoma in a Japanese population.

International journal of cancer - 15 Mar 2006

Sakamoto Tatsuhiko, Hara Megumi, Higaki Yasuki, Ichiba Masayoshi, Horita Mikako, Mizuta Toshihiko, Eguchi Yuichiro, Yasutake Tsutomu, Ozaki Iwata, Yamamoto Kyosuke, Onohara Shingo, Kawazoe Seiji, Shigematsu Hirohisa, Koizumi Shunzo, Tanaka Keitaro

Abstract excerpt

Although alcohol intake as well as hepatitis viruses has been associated with hepatocellular carcinoma (HCC), gene-alcohol interactions on HCC risk remain to be elucidated. We conducted a case-control study to examine whether polymorphisms of alcohol dehydrogenase 2 (ADH2) and aldehyde dehydrogenase 2 (ALDH2) modified the HCC risk depending on the amount of alcohol intake. ADH2 and ALDH2 genotyping was performed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Dehydrogenase
Share to Alcohol Drinking

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aldehyde Dehydrogenase

Share to Aldehyde Dehydrogenase, Mitochondrial

Share to Carcinoma, Hepatocellular

Share to Liver Neoplasms

Share to Surveys and Questionnaires

Source

Identifiers

PMID: 16187278
DOI: 10.1002/ijc.21505

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of alcohol consumption and gene polymorphisms of ADH2 and ALDH2 on hepatocellular carcinoma in a Japanese population.PMID 16187278Read ↗

Relationship between alcohol drinking, ADH2 and ALDH2 genotypes, and risk for hepatocellular carcinoma in Japanese.Semantic proximity Read ↗

Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotypes, alcohol drinking and the risk of primary hepatocellular carcinoma in a Chinese population.Semantic proximity Read ↗

Gene-gene and gene-environment interactions between alcohol drinking habit and polymorphisms in alcohol-metabolizing enzyme genes and the risk of head and neck cancer in Japan.Semantic proximity Read ↗

Polymorphisms of ethanol metabolizing enzyme genes and alcoholism.Semantic proximity Read ↗

Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and the risk of hepatocellular carcinoma.Semantic proximity Read ↗

Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics.Semantic proximity Read ↗

Role of ALDH2 in Hepatic Disorders: Gene Polymorphism and Disease PathogenesisSemantic proximity Read ↗

Genetic polymorphisms of ALDH2 and ADH2 are not associated with risk of hepatocellular carcinoma among East Asians.Semantic proximity Read ↗

High incidence of ADH2*1/ALDH2*1 genes among Japanese alcohol dependents and patients with alcoholic liver diseaseSemantic proximity Read ↗

Genetic polymorphisms of alcohol and aldehyde dehydrogenases, and drinking, smoking and diet in Japanese men with oral and pharyngeal squamous cell carcinoma.Semantic proximity Read ↗

Do alcohol-metabolizing enzyme gene polymorphisms increase the risk of alcoholism and alcoholic liver disease?Semantic proximity Read ↗

High incidence of ADH2*1/ALDH2*1 genes among Japanese alcohol dependents and patients with alcoholic liver disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.