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Article

Cyclin D1 genotype and expression in sporadic hemangioblastomas.

Journal of neuro-oncology - 1 Sept 2005

Gijtenbeek Johanna M M, Boots-Sprenger Sandra H E, Franke Barbara, Wesseling Pieter, Jeuken Judith W M

Abstract excerpt

Central nervous system (CNS) hemangioblastomas are highly-vascularized tumors occurring in sporadic form or as a manifestation of von Hippel-Lindau disease (VHL). The VHL protein (pVHL) regulates various target genes, one of which is the CCND1 gene, encoding cyclin D1, a protein that plays a critical role in the control of the cell cycle. Overexpression of cyclin D1 is found in many cancers. The CCND1 gene...

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Source

Identifiers

PMID: 16187023
DOI: 10.1007/s11060-004-7326-z

Genes

CCND1
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Cyclin D1 genotype and expression in sporadic hemangioblastomas.PMID 16187023Read ↗

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