Article
Cyclin D1 gene G870A variants and primary brain tumors.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Zeybek Umit, Yaylim Ilhan, Ozkan Nazli Ezgi, Korkmaz Gurbet, Turan Saime, Kafadar Didem, Cacina Canan, Kafadar Ali Metin
Abstract excerpt
Alterations of cyclin D1, one of the main regulators of the cell cycle, are known to be involved in various cancers. The CCDN1 G870A polymorphism causes production of a truncated variant with a shorter half-life and thus thought to impact the regulatory effect of CCDN1. The aim of the present study was to contribute to existing results to help to determine the prognostic value of this specific gene variant and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
