Article
High-Resolution Analysis of Genomic Alterations and Human Papillomavirus Integration in Anal Intraepithelial Neoplasia
20 Sept 2005
Abstract excerpt
Anal intraepithelial neoplasia (AIN) is the likely precursor to anal cancer. AIN is associated with human papillomavirus (HPV) infection, and HPV-associated genomic instability may play an important role in the progression of squamous intraepithelial neoplasia to cancer. Microarray-based comparative genome hybridization (aCGH) was performed on DNA from AIN specimens to determine the host genomic alterations and...
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