Article
Mapping of a macular drusen susceptibility locus in rhesus macaques to the homologue of human chromosome 6q14-15.
Experimental eye research - 1 Oct 2005
Singh Krishna K, Ristau Steven, Dawson William W, Krawczak Michael, Schmidtke Jörg
Abstract excerpt
Rhesus macaques (Macaca mulatta) are a natural model for retinal drusen formation. The present study aimed at clarifying whether chromosomal regions homologous to candidate genes for drusen formation and progression in humans are also associated with a drusen phenotype in rhesus macaques. Some 42 genetic markers from seven chromosomal regions implicated in macular degeneration syndromes in humans were tested for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
