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Article

Indirect exclusion of four candidate genes for generalized progressive retinal atrophy in several breeds of dogs.

Journal of negative results in biomedicine - 29 Nov 2006

Lippmann Tanja, Pasternack Sandra M, Kraczyk Britta, Dudek Sabine E, Dekomien Gabriele

Abstract excerpt

BACKGROUND: Generalized progressive retinal atrophy (gPRA) is a hereditary ocular disorder with progressive photoreceptor degeneration in dogs. Four retina-specific genes, ATP binding cassette transporter retina (ABCA4), connexin 36 (CX36), c-mer tyrosin kinase receptor (MERTK) and photoreceptor cell retinol dehydrogenase (RDH12) were investigated in order to identify mutations leading to autosomal recessive (ar)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17134500
DOI: 10.1186/1477-5751-5-19
PMCID: PMC1716180

Genes

ABCA4
MERTK
RDH12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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