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Article

Early-Onset Macular Degeneration with Drusen in a Cynomolgus Monkey (Macaca fascicularis) Pedigree: Exclusion of 13 Candidate Genes and Loci

26 Jan 2005

Abstract excerpt

PURPOSE: To describe hereditary macular degeneration observed in the cynomolgus monkey (Macaca fascicularis), which shares phenotypic features with age-related macular degeneration in humans, and to test the involvement of candidate gene loci by mutation screening and linkage analysis. METHODS: Ophthalmic examinations with fundus photography, fluorescein angiography (FA), indocyanine green angiography (IA),...

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PMID: 15671300
DOI: 10.1167/iovs.04-1031

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