Article
Fulminant hepatitis related to transmission of hepatitis B variants with precore mutations between spouses.
Hepatology (Baltimore, Md.) - 1 Jul 1992
Yotsumoto S, Kojima M, Shoji I, Yamamoto K, Okamoto H, Mishiro S
Abstract excerpt
A precore defective variant of hepatitis B virus has been indicated to cause fulminant hepatitis in various instances such as intrahospital outbreaks or mother-to-child transmission of hepatitis B virus. To learn whether similar variants are involved in interspouse transmission, we analyzed three...
Topics
- Base Sequence
- Cloning, Molecular
- Codon
- DNA, Viral
- Defective Viruses
- Female
- Genes, Viral
- Genetic Variation
- Genotype
- Hepatitis B
- Hepatitis B Core Antigens
- Hepatitis B virus
- Humans
- Longitudinal Studies
- Male
- Molecular Sequence Data
- Mutation
- Nuclear Family