Article
Molecular analysis of the interspousal transmission of hepatitis B virus in two Japanese patients who acquired fulminant hepatitis B after 50 and 49 years of marriage.
Journal of medical virology - 1 Nov 2014
Okamoto Daisuke, Nakayama Haruo, Ikeda Tomoyuki, Ikeya Shinichi, Nagashima Shigeo, Takahashi Masaharu, Sugai Yoshiki, Okamoto Hiroaki
Abstract excerpt
A 71-year-old (C1I) and 69-year-old (C2I) Japanese female contracted fulminant hepatitis B after 50 and 49 years of marriage, respectively. Both index cases exhibited high levels of anti-HBc IgM antibodies (24.2 and 31.5 S/CO, respectively), suggestive of acute hepatitis B virus (HBV) infection, although they had no discernible risk factors for HBV infection, except for chronically HBV-infected spouses with...
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