Article
Contribution of dppA to urease activity in Helicobacter pylori 26695.
Helicobacter - 1 Oct 2005
Davis Gregg S, Mobley Harry L T
Abstract excerpt
BACKGROUND: The gastric pathogen Helicobacter pylori produces urease in amounts up to 10% of its cell protein. This enzyme, which catalyzes the hydrolysis of urea to ammonia and carbon dioxide, protects the bacterium from gastric acid. Urease, a nickel metalloenzyme, requires active uptake of nickel ions from the environment to maintain its activity. NixA is a nickel transport protein that resides in the...
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