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Article

Helicobacter pylori ABC transporter: effect of allelic exchange mutagenesis on urease activity.

Journal of bacteriology - 1 Sept 1997

Hendricks J K, Mobley H L

Abstract excerpt

Helicobacter pylori urease requires nickel ions in the enzyme active site for catalytic activity. Nickel ions must, therefore, be actively acquired by the bacterium. NixA (high-affinity nickel transport protein)-deficient mutants of H. pylori retain significant urease activity, suggesting the presence of alternate nickel transporters. Analysis of the nucleotide sequence of the H. pylori genome revealed a homolog...

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Identifiers

PMID: 9294450
DOI: 10.1128/jb.179.18.5892-5902.1997
PMCID: PMC179482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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