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Article

Phenotyping and genotyping studies of thiopurine S-methyltransferase in Kazaks.

Pharmaceutical research - 1 Oct 2005

Wei Hong, Zhou Shufeng, Li Chengrong, Zhang Jianping, Wu Jueheng, Huang Min

Abstract excerpt

OBJECTIVE: This study was conducted to investigate the thiopurine S-methyltransferase (TPMT) activity distribution and gene mutations in Kazaks, and compared the results with those of other ethnic groups. METHODS: Erythrocyte TPMT activity was measured in Kazaks (n = 327) via a validated high-performance liquid chromatography assay. Polymerase chain reaction-based methods were used to analyze three commonly...

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Source

Identifiers

PMID: 16180135
DOI: 10.1007/s11095-005-7095-1

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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