Article
Linkage disequilibrium mapping of quantitative-trait Loci by selective genotyping.
American journal of human genetics - 1 Oct 2005
Chen Zehua, Zheng Gang, Ghosh Kaushik, Li Zhaohai
Abstract excerpt
The principles of linkage disequilibrium mapping of dichotomous diseases can be well applied to the mapping of quantitative-trait loci through the method of selective genotyping. In 1999, M. Slatkin considered a truncation selection (TS) approach. We propose in this report an extended TS approach and an extreme-rank-selection (ERS) approach. The properties of these selection approaches are studied analytically....
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