Article
Optimal designs for linkage disequilibrium mapping and candidate gene association tests in livestock populations.
Genetics - 1 Jan 2004
Stella Alessandra, Boettcher Paul J
Abstract excerpt
Simulation was used to evaluate the performance of different selective genotyping strategies when using linkage disequilibrium across large half-sib families to position a QTL within a previously defined genomic region. Strategies examined included standard selective genotyping and different approaches of discordant and concordant sib selection applied to arbitrary or selected families. Strategies were compared...
Topics
- Alleles
- Animals
- Animals, Domestic
- Cattle
- Chromosome Mapping
- Female
- Gene Frequency
- Genetic Markers
- Genetic Techniques
- Genotype
- Linkage Disequilibrium
- Male
- Models, Genetic
- Phenotype
- Quantitative Trait Loci
