Article
Genome-wide linkage analysis for aggressive prostate cancer in Utah high-risk pedigrees.
The Prostate - 1 May 2007
Christensen G B, Camp N J, Farnham J M, Cannon-Albright L A
Abstract excerpt
BACKGROUND: It has been proposed that studying alternative phenotypes, such as tumor aggressiveness, may be a solution for overcoming the apparent heterogeneity that has hindered the identification of prostate cancer (PC) genes. We present the results of a genome-scan for predisposition to aggressive PC using the Utah high-risk pedigree resource. METHODS: We identified 259 subjects with aggressive PC in 57...
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