Article
Replication of prostate cancer risk loci in a Japanese case-control association study.
Journal of the National Cancer Institute - 7 Oct 2009
Yamada Hiroki, Penney Kathryn L, Takahashi Hiroyuki, Katoh Takahiko, Yamano Yuko, Yamakado Minoru, Kimura Takahiro, Kuruma Hidetoshi, Kamata Yuko, Egawa Shin, Freedman Matthew L
Abstract excerpt
BACKGROUND: Two prostate cancer genome-wide scans in populations of European ancestry identified several genetic variants that are strongly associated with prostate cancer risk. The effect of these risk variants and their cumulative effect in other populations are unknown. METHODS: We evaluated the association of 23 risk single-nucleotide polymorphisms (SNPs) with prostate cancer risk and clinical covariates...
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