Article
Genomewide scan for prostate cancer-aggressiveness loci.
American journal of human genetics - 1 Jul 2000
Witte J S, Goddard K A, Conti D V, Elston R C, Lin J, Suarez B K, Broman K W, Burmester J K, Weber J L, Catalona W J
Abstract excerpt
The aggressiveness of prostate cancer (PCa) varies widely: some tumors progress to invasive, potentially life-threatening disease, whereas others stay latent for the remainder of an individual's lifetime. The mechanisms resulting in this variability are not yet understood, but they are likely to involve both genetic and environmental influences. To investigate genetic factors, we conducted a genomewide linkage...
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