Article
Multilocus markers for mouse genome analysis: PCR amplification based on single primers of arbitrary nucleotide sequence.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1992
Nadeau J H, Bedigian H G, Bouchard G, Denial T, Kosowsky M, Norberg R, Pugh S, Sargeant E, Turner R, Paigen B
Abstract excerpt
Polymerase chain reaction (PCR) based on single primers of arbitrary nucleotide sequence provides a powerful marker system for genome analysis because each primer amplifies multiple products, and cloning, sequencing, and hybridization are not required. We have evaluated this typing system for the...
Topics
- Animals
- Base Composition
- Base Sequence
- DNA
- Genetic Linkage
- Genetic Markers
- Genetic Variation
- Genome
- Magnesium
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Polymerase Chain Reaction
- Templates, Genetic