Article
Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research.
Genetics - 1 Dec 2020
Sigmon John Sebastian, Blanchard Matthew W, Baric Ralph S, Bell Timothy A, Brennan Jennifer, Brockmann Gudrun A, Burks A Wesley, Calabrese J Mauro, Caron Kathleen M, Cheney Richard E, Ciavatta Dominic, Conlon Frank, Darr David B, Faber James, Franklin Craig, Gershon Timothy R, Gralinski Lisa, Gu Bin, Gaines Christiann H, Hagan Robert S, Heimsath Ernest G, Heise Mark T, Hock Pablo, Ideraabdullah Folami, Jennette J Charles, Kafri Tal, Kashfeen Anwica, Kulis Mike, Kumar Vivek, Linnertz Colton, Livraghi-Butrico Alessandra, Lloyd K C Kent, Lutz Cathleen, Lynch Rachel M, Magnuson Terry, Matsushima Glenn K, McMullan Rachel, Miller Darla R, Mohlke Karen L, Moy Sheryl S, Murphy Caroline E Y, Najarian Maya, O'Brien Lori, Palmer Abraham A, Philpot Benjamin D, Randell Scott H, Reinholdt Laura, Ren Yuyu, Rockwood Steve, Rogala Allison R, Saraswatula Avani, Sassetti Christopher M, Schisler Jonathan C, Schoenrock Sarah A, Shaw Ginger D, Shorter John R, Smith Clare M, St Pierre Celine L, Tarantino Lisa M, Threadgill David W, Valdar William, Vilen Barbara J, Wardwell Keegan, Whitmire Jason K, Williams Lucy, Zylka Mark J, Ferris Martin T, McMillan Leonard, Manuel de Villena Fernando Pardo
Abstract excerpt
The laboratory mouse is the most widely used animal model for biomedical research, due in part to its well-annotated genome, wealth of genetic resources, and the ability to precisely manipulate its genome. Despite the importance of genetics for mouse research, genetic quality control (QC) is not standardized, in part due to the lack of cost-effective, informative, and robust platforms. Genotyping arrays are...
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