Article
Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse.
Nature genetics - 1 Apr 2000
Lindblad-Toh K, Winchester E, Daly M J, Wang D G, Hirschhorn J N, Laviolette J P, Ardlie K, Reich D E, Robinson E, Sklar P, Shah N, Thomas D, Fan J B, Gingeras T, Warrington J, Patil N, Hudson T J, Lander E S
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) have been the focus of much attention in human genetics because they are extremely abundant and well-suited for automated large-scale genotyping. Human SNPs, however, are less informative than other types of genetic markers (such as simple-sequence length polymorphisms or microsatellites) and thus more loci are required for mapping traits. SNPs offer similar advantages for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.