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Article

Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms.

Oncogene - 5 Jan 2006

Anderson C J, Hoare S F, Ashcroft M, Bilsland A E, Keith W N

Abstract excerpt

Basal telomerase activity is dependent on expression of the hTERT and hTR genes and upregulation of telomerase gene expression is associated with tumour development. It is therefore possible that signal transduction pathways involved in tumour development and features of the tumour environment itself may influence telomerase gene regulation. The majority of solid tumours contain regions of hypoxia and it has...

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Identifiers

PMID: 16170363
DOI: 10.1038/sj.onc.1209011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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