Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypoxia-Inducible Factor 1 Mediates Upregulation of Telomerase (hTERT)

15 Jun 2004

Abstract excerpt

Hypoxia occurs during the development of the placenta in the first trimester and correlates with both trophoblast differentiation and the induction of telomerase activity through hTERT expression. We sought to determine the mechanism of regulation of hTERT expression during hypoxia. We show that hypoxia-inducible factor 1alpha (HIF-1alpha) and hTERT expression in the human placenta decrease with gestational age...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neonatal Respiratory Health Research
Share to Pregnancy and preeclampsia studies
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15199161
DOI: 10.1128/mcb.24.13.6076-6083.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypoxia-Inducible Factor 1 Mediates Upregulation of Telomerase (hTERT)PMID 15199161Read ↗

Expression, Ontogeny, and Regulation of Hypoxia-Inducible Transcription Factors in the Human Placenta1Semantic proximity Read ↗

Human Placental Hypoxia-Inducible Factor-1α Expression Correlates with Clinical Outcomes in Chronic Hypoxia in VivoSemantic proximity Read ↗

Trophoblast-Specific Expression of Hif-1α Results in Preeclampsia-Like Symptoms and Fetal Growth RestrictionSemantic proximity Read ↗

Dysregulation of hypoxia-inducible factor-1α (Hif1α) expression in the Hmox1-deficient placentaSemantic proximity Read ↗

Expression of hypoxia-inducible factor 1: mechanisms and consequencesSemantic proximity Read ↗

Induction of glucose transporter 1 expression through hypoxia-inducible factor 1α under hypoxic conditions in trophoblast-derived cellsSemantic proximity Read ↗

Hypoxia-inducible factor 1 signaling drives placental aging and can provoke preterm laborSemantic proximity Read ↗

Hypoxia-inducible factor 1 signaling drives placental aging and can provoke preterm laborSemantic proximity Read ↗

The Role of Hypoxia and Hypoxia-Inducible Factor-1Alpha in Preeclampsia PathogenesisSemantic proximity Read ↗

Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation.Semantic proximity Read ↗

Trophoblast survival signaling during human placentation requires HIF-induced transcription of HSP70Semantic proximity Read ↗

Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restrictionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.