Article
Evaluation of the mitochondrial respiratory chain and oxidative phosphorylation system using yeast models of OXPHOS deficiencies.
Current protocols in human genetics - 1 Oct 2009
Fontanesi Flavia, Diaz Francisca, Barrientos Antoni
Abstract excerpt
The oxidative phosphorylation (OXPHOS) system consists of five multimeric complexes embedded in the mitochondrial inner membrane. They work in concert to drive the aerobic synthesis of ATP. Mitochondrial and nuclear DNA mutations affecting the accumulation and function of these enzymes are the mo...
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