Article
Interacting contribution of the five polymorphisms in three genes of Hsp70 family to essential hypertension in Uygur ethnicity.
Cell stress & chaperones - 1 Jul 2009
Li Jin-Xin, Tang Bao-Peng, Sun Hui-Ping, Feng Min, Cheng Zu-Heng, Niu Wen-Quan
Abstract excerpt
Experimental evidence suggesting that heat shock protein 70 (Hsp70) gene or associated genes are responsible for the pathophysiology of hypertension is accumulating. In this study, we focused on five polymorphisms in three genes (HSPA1A, HSPA1B, and HSPA1L) of Hsp70 family to explore the genetic contribution, alone and in combination, of these polymorphisms to essential hypertension risk in a Uygur population....
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