Article

Reduced mineralization potential of osteoblasts in adolescent idiopathic scoliosis: intrinsic dysfunction and crosstalk with TLR-activated chondrocytes

2025-10-12

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Patients with Adolescent Idiopathic Scoliosis (AIS) present with facet joint osteoarthritis, which may contribute to curve progression. While inflammatory mediators from degenerative cartilage are known to influence osteoclast activity, their effects on osteoblast function in AIS remain unclear. <bold>Methods</bold> Primary facet joint osteoblasts were isola...

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Literature Corpus work: 6fedff32-9a68-54d2-ab90-92578a7da470
DOI: 10.21203/rs.3.rs-7602845/v1

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