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Article

Lactate racemization as a rescue pathway for supplying D-lactate to the cell wall biosynthesis machinery in Lactobacillus plantarum.

Journal of bacteriology - 1 Oct 2005

Goffin Philippe, Deghorain Marie, Mainardi Jean-Luc, Tytgat Isabelle, Champomier-Vergès Marie-Christine, Kleerebezem Michiel, Hols Pascal

Abstract excerpt

Lactobacillus plantarum is a lactic acid bacterium that produces d- and l-lactate using stereospecific NAD-dependent lactate dehydrogenases (LdhD and LdhL, respectively). However, reduction of glycolytic pyruvate by LdhD is not the only pathway for d-lactate production since a mutant defective in this activity still produces both lactate isomers (T. Ferain, J. N. Hobbs, Jr., J. Richardson, N. Bernard, D. Garmyn,...

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Identifiers

PMID: 16166538
DOI: 10.1128/JB.187.19.6750-6761.2005
PMCID: PMC1251571

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Source receipt: pubmed, retrieved 7 Sept 2026.

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