Article
High-level production of the low-calorie sugar sorbitol by Lactobacillus plantarum through metabolic engineering.
Applied and environmental microbiology - 1 Mar 2007
Ladero Victor, Ramos Ana, Wiersma Anne, Goffin Philippe, Schanck André, Kleerebezem Michiel, Hugenholtz Jeroen, Smid Eddy J, Hols Pascal
Abstract excerpt
Sorbitol is a low-calorie sugar alcohol that is largely used as an ingredient in the food industry, based on its sweetness and its high solubility. Here, we investigated the capacity of Lactobacillus plantarum, a lactic acid bacterium found in many fermented food products and in the gastrointestinal tract of mammals, to produce sorbitol from fructose-6-phosphate by reverting the sorbitol catabolic pathway in a...
Topics
- Bacterial Proteins
- Carbohydrates
- Fermentation
- Fructosephosphates
- Gene Expression
- Genetic Engineering
- Glucose
- Hydrogen-Ion Concentration
- L-Lactate Dehydrogenase
- Lactobacillus plantarum
- Magnetic Resonance Spectroscopy
- Mannitol