Article
Inter-strain variance in late phase of erythematous reaction or leg contracture after local irradiation among three strains of mice.
Cancer detection and prevention - 1 Jan 2005
Noda Shuhei, Iwakawa Mayumi, Ohta Toshie, Iwata Masaru, Yang Minfu, Goto Miyako, Tanaka Hiroko, Harada Yoshinobu, Imai Takashi
Abstract excerpt
AIM: To gain insights into inter-strain differences in radiosensitivity. METHODS: Mice of inbred strains, A/J, C57BL/6J, and C3H/HeMs, were irradiated at graded doses ranging from 20 to 60 Gy. Skin reaction and leg contraction were observed for a period of 230 days and between 175 and 350 days, respectively. Gene expressions in leg skin tissue were quantified by quantitative RT-PCR assay at 1, 12 and 72 h after...
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