Article
Genetic variation in low-dose UV-induced suppression of contact hypersensitivity and in the skin photocarcinogenesis response.
The Journal of investigative dermatology - 1 Dec 1997
Yamawaki M, Katiyar S K, Anderson C Y, Tubesing K A, Mukhtar H, Elmets C A
Abstract excerpt
Two of the major cutaneous consequences of ultraviolet (UV) radiation exposure are immunosuppression and the development of skin cancer. This study examined whether these effects are genetically determined. Suppression of contact hypersensitivity by local, low-dose UV radiation was examined in what have been termed "UV-susceptible" and "UV-resistant" strains of mice. C3H/HeJ mice ("UV resistant") were resistant...
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