Article
Lipid peroxidation induced by carbon tetrachloride and its inhibition by antioxidant as evaluated by an oxidative stress marker, HODE.
Toxicology and applied pharmacology - 1 Oct 2005
Yoshida Yasukazu, Itoh Nanako, Hayakawa Mieko, Piga Rosaria, Cynshi Osamu, Jishage Kou-ichi, Niki Etsuo
Abstract excerpt
We have recently proposed total hydroxyoctadecadienoic acid (HODE) as a biomarker for oxidative stress in vivo. The biological samples such as plasma, urine, and tissues were first reduced and then saponified to convert the oxidation products of linoleate to HODE. In the present study, this method was applied to measure the oxidative damage induced by the administration of carbon tetrachloride to mice and also to...
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