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Article

A role for topoisomerase III in a recombination pathway alternative to RuvABC.

Molecular microbiology - 1 Oct 2005

Lopez Christopher R, Yang Shirley, Deibler Richard W, Ray Starlight A, Pennington Jeanine M, Digate Russell J, Hastings P J, Rosenberg Susan M, Zechiedrich E Lynn

Abstract excerpt

The physiological role of topoisomerase III is unclear for any organism. We show here that the removal of topoisomerase III in temperature sensitive topoisomerase IV mutants in Escherichia coli results in inviability at the permissive temperature. The removal of topoisomerase III has no effect on the accumulation of catenated intermediates of DNA replication, even when topoisomerase IV activity is removed. Either...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16164551
DOI: 10.1111/j.1365-2958.2005.04812.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A role for topoisomerase III in a recombination pathway alternative to RuvABC.PMID 16164551Read ↗

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