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Article

Association of polymorphisms in pulmonary surfactant protein A1 and A2 genes with high-altitude pulmonary edema.

Chest - 1 Sept 2005

Saxena Shweta, Kumar Ratan, Madan Taruna, Gupta Vanita, Muralidhar Kambadur, Sarma Puranam U

Abstract excerpt

STUDY OBJECTIVES: A potential pathogenetic cofactor for the development of high-altitude pulmonary edema (HAPE) is an increase in capillary permeability, which could occur as a result of an inflammatory reaction and/or free-radical-mediated injury to the lung. Pulmonary surfactant protein A (SP-A), the most abundant surfactant protein, has potent antioxidant properties and protects unsaturated phospholipids and...

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Source

Identifiers

PMID: 16162765
DOI: 10.1378/chest.128.3.1611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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