Article
Case-control Association Study of Autoimmunity Associated Variants in PDCD1 and Juvenile Idiopathic Arthritis.
Current rheumatology reviews - 1 Jan 2017
Tejeda Christina, Broadaway Alaine K, Ombrello Michael J, Brown Milton R, Ponder Lori A, Pichavant Mina Rohani, Wang Gabriel, Angeles-Han Sheila, Hersh Aimee, Bohnsack John, Conneely Karen N, Epstein Michael, Prahalad Sampath
Abstract excerpt
PURPOSE: Variants in the gene encoding Programmed Cell Death-1 (PDCD1) have been associated with susceptibility to Systemic Lupus Erythematosus and other autoimmune diseases. Given that clinically distinct autoimmune phenotypes share common genetic susceptibility factors, variants in PDCD-1 were tested for a possible association with Juvenile Idiopathic Arthritis (JIA). METHODS: Four Single Nucleotide...
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