Article
PADI4 (rs2240340), PDCD1 (rs10204525), and CTLA4 (231775) gene polymorphisms and polyarticular juvenile idiopathic arthritis.
British journal of biomedical science - 1 Jul 2020
Ali M A, Abdelaziz A, Ali M, Abonar A, Hanafy M, Hussein H, Shabana H, Abd El-Hmid R, Kaddafy S
Abstract excerpt
BACKGROUND: Certain single nucleotide polymorphisms (SNPs) in genes such as PADI4 (coding for peptidyl arginine deiminase 4), PDCD1 (coding for programmed cell death 1), and CTLA4 (coding for cytotoxic T-lymphocyte-associated protein 4) are linked to rheumatoid arthritis (RA). However, links between SNPs rs2240340, rs10204525 and rs231775 in PADI4, PDCD1 and CTLA4 respectively, and juvenile idiopathic arthritis...
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