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Kisspeptin and its Receptor: New Gatekeepers of Puberty

7 Sept 2005

Abstract excerpt

The recent finding that the hormone kisspeptin plays a pivotal role in the onset of puberty is one of the biggest discoveries in human reproductive biology in 30 years. Mutations in the receptor for kisspeptin cause humans and mice to fail to reach puberty and to be sterile. It is the first time since the identification of gonadotrophin-releasing hormone that a single gene is found to have such a dramatic effect...

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PMID: 16159382
DOI: 10.1111/j.1365-2826.2005.01357.x

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Related research

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