Article
Functional and immunophenotypic modifications induced by interleukin-2 did not predict response to therapy in patients with renal cell carcinoma.
Journal of biological response modifiers - 1 Apr 1990
Favrot M C, Combaret V, Negrier S, Philip I, Thiesse P, Freydel C, Bijmann J T, Franks C R, Mercatello A, Philip T
Abstract excerpt
Twenty-five patients with renal cell carcinoma were treated with continuous infusion of IL-2 (3 x 10(6) units/m2/day) with or without lymphokine-activated killer (LAK) cells; 5 responded to therapy. Functional and immunophenotypic modifications of the peripheral blood lymphocytes (PBLs) did not p...
Topics
- Adult
- Aged
- B-Lymphocytes
- CD4-Positive T-Lymphocytes
- Carcinoma, Renal Cell
- Cell Division
- Cells, Cultured
- Humans
- Immunotherapy
- Interleukin-2
- Kidney Neoplasms
- Killer Cells, Lymphokine-Activated
- Killer Cells, Natural
- Leukocyte Count