Article
Functional and immunophenotypic modifications induced by interleukin-2 did not predict response to therapy in patients with renal cell carcinoma.
Journal of biological response modifiers - 1 Apr 1990
Favrot M C, Combaret V, Negrier S, Philip I, Thiesse P, Freydel C, Bijmann J T, Franks C R, Mercatello A, Philip T
Abstract excerpt
Twenty-five patients with renal cell carcinoma were treated with continuous infusion of IL-2 (3 x 10(6) units/m2/day) with or without lymphokine-activated killer (LAK) cells; 5 responded to therapy. Functional and immunophenotypic modifications of the peripheral blood lymphocytes (PBLs) did not predict response to therapy. Systemic administration of interleukin-2 (IL-2) during 5 days caused a preferential...
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