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Article

The factor V Leiden mutation, high factor VIII, and high plasminogen activator inhibitor activity: etiologies for sporadic miscarriage.

Metabolism: clinical and experimental - 1 Oct 2005

Glueck Charles J, Pranikoff Joel, Aregawi Dawit, Haque Mofiz, Zhu Binghua, Tracy Trent, Wang Ping

Abstract excerpt

We hypothesized that the thrombophilic G1691A factor V Leiden gene mutation was a common significant cause of sporadic first trimester miscarriage. We compared thrombophilia and hypofibrinolysis in 92 women (85 white, 5 black, 2 other) with 1 or more pregnancies and 1 miscarriage (143 live births, 92 miscarriages) (cases) and in 380 female controls (355 white, 21 black, 4 other) with 1 or more pregnancies and 0...

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Source

Identifiers

PMID: 16154434
DOI: 10.1016/j.metabol.2005.04.024

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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