Article
Prevalence of coagulation factor XIII and plasminogen activator inhibitor-1 gene polymorphisms among Egyptian women suffering from unexplained primary recurrent miscarriage.
Journal of reproductive immunology - 1 Jun 2014
Elmahgoub Iman Rifaat, Afify Reham Abdelaleem, Abdel Aal Asmaa Ahmed, El-Sherbiny Walid Sayed
Abstract excerpt
Recurrent miscarriage (RM) is an obstetric challenge. Polymorphisms of factor XIII (FXIII) and plasminogen activator inhibitor-1 (PAI-1) may cause an imbalance between coagulation and fibrinolysis that can end in RM. The aim of the work was to determine the prevalence of FXIII Val34Leu and PAI-1 4G/5G gene polymorphisms in Egyptian women presenting with unexplained primary first trimester RM. Genotyping of 120...
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